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Apolipoproteins characterize a heterogeneous group of lipoproteins found in the brain
and circulation that facilitate the transport of hydrophobic compounds through aqueous
fluids. We sought to determine whether apolipoproteins previously implicated in Alzheimer’s
disease are associated with hippocampal volume and white matter lesion volume. Further,
we examined whether subspecies of apolipoproteins, based on the presence or absence
of other apolipoproteins, provide information about Alzheimer’s pathophysiology beyond
their overall concentrations.
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